Onglyza and Kombiglyze XR Linked to Pancreatic Cancer and Heart Failure

On Behalf of | Sep 18, 2015 | Uncategorized

Onglyza and Kombiglyze XR Linked to Pancreatic Cancer

For adults with Type 2 diabetes, there is a range of drug regimens available to control the condition. However, two drugs have recently been linked to acute pancreatitis leading to precancerous changes and an increased risk of heart failure.

Onglyza or Kombiglyze XR both belong to a class of Type 2 diabetes medications called incretin mimetics. Both contain the active ingredient saxagliptin, and work by increasing the amount of incretin released by the intestine. Incretin plays an important role in regulating the amount of insulin secreted by the pancreas.

Type 2 diabetics taking these drugs are at risk

According to the Food and Drug Administration, there have been reports of acute pancreatitis in patients taking Onglyza. Saxagliptin should not be prescribed to people who have a history of pancreatitis (inflammation of the pancreas) because it is not known whether the medication can increase the risk for the disease.

In 2014, the FDA issued a safety alert after a study found that Onglyza was responsible for a 27% increase in the risk of hospitalization for heart failure. The drug is still available for sale, and is still being prescribed despite the known risks.

Your doctor should be aware of your family history, and should not prescribe either of these drugs if you have any risk factors for pancreatitis or a heart condition. However, some doctors may not be aware of the adverse side effects of these drugs. If you are taking Onglyza or Kombiglyze XR for Type 2 diabetes, you should discuss alternative treatment options with your doctor.

If you or someone you know is currently taking or has taken Onglyza or Kombiglyze XR for Type 2 diabetes, you should have a full physical examination as soon as possible and talk to your doctor about alternative treatments.

You may be entitled to compensation if you have suffered any injuries or damages while taking these medications. Our experienced medical malpractice and defective medical device attorneys can get you the compensation you deserve. Visit the Crandall & Pera Law offices in Ohio or Kentucky, or contact us today for a consultation with an experienced defective drug litigation attorney.

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